Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537153 | 0.77 | ALDH1A1 (0.62) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL16091656 | 0.74 | MAPT (0.53) | MAPTLMNAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL12322876 | 0.72 | MAPT (0.52) | MAPTLMNAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL19156312 | 0.70 | MAPT (0.42) | MAPTLMNAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL10216413 | 0.70 | MAPT (0.44) | MAPTLMNAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL21027734 | 0.68 | MAPT (0.43) | MAPTLMNAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL24329142 | 0.66 | SLC5A1 (0.54) | MAPTLMNAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL24329076 | 0.66 | PADI4 (0.44) | MAPTLMNAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL10865194 | 0.65 | MAPT (0.44) | MAPTLMNAHSD17B10ALDH1A1KMT2A | |
| SCHEMBL12374703 | 0.65 | KDM4E (0.42) | LMNAALDH1A1SMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022080346-A1 | NOVEL NITROGEN-CONTAINING CYCLIC COMPOUND AND APPLICATION THEREOF | 国立大学法人佐賀大学 | 2022-04-21 | — | — | WO | disclosed |