Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12668867 | 1.00 | ACACB (0.48) | ACACBHDAC1HDAC6FPR2EPHX1 | |
| SCHEMBL22133087 | 0.88 | EPHX1 (0.49) | ACACBHDAC1HDAC6FPR2EPHX1 | |
| SCHEMBL16203422 | 0.86 | FPR2 (0.54) | HDAC1HDAC6FPR2CTSSCTSK | |
| SCHEMBL15703612 | 0.86 | FPR2 (0.54) | HDAC1HDAC6FPR2CTSSCTSK | |
| SCHEMBL9886030 | 0.84 | ACACB (0.46) | ACACBMEN1NPC1KMT2A | |
| SCHEMBL16327905 | 0.84 | ESR1 (0.40) | EPHX1CTSSCTSKKMT2AMME | |
| SCHEMBL7637685 | 0.84 | ESR1 (0.56) | MMETAAR1 | |
| SCHEMBL14942927 | 0.84 | ESR1 (0.56) | MMETAAR1 | |
| SCHEMBL8231892 | 0.84 | ESR1 (0.56) | MMETAAR1 | |
| SCHEMBL12668874 | 0.84 | ACACB (0.46) | ACACBMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079428-A1 | LINEAR APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-04-21 | — | — | WO | disclosed |