SCHEMBL24329331

SCHEMBL24329331

BN1CCC(c2cccc(OCc3cc(C)c(C(=O)C4CC4)cc3F)n2)CC1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25957827 0.91 GLP1R (0.52) GLP1R
SCHEMBL25957798 0.89 GLP1R (0.46) GLP1R
SCHEMBL29555345 0.87 GLP1R (0.47) GLP1R
SCHEMBL24329808 0.87 GLP1R (0.47) GLP1R
SCHEMBL24329329 0.87 GLP1R (0.47) GLP1R
SCHEMBL25957852 0.86 GLP1R (0.45) GLP1R
SCHEMBL25955940 0.81 GLP1R (0.62) GLP1R
SCHEMBL25952433 0.80 GLP1R (0.53) GLP1R
SCHEMBL25959193 0.80 GLP1R (0.60) GLP1R
SCHEMBL25960918 0.80 GLP1R (0.72) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022078152-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF 杭州中美华东制药有限公司 2022-04-21 WO disclosed