SCHEMBL24329334

SCHEMBL24329334

Cc1ccc(Br)cc1OC1CC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 1/20 0.42
NPY2R P49146 1/20 0.42
SLC6A4 P31645 4/20 0.40
HTR6 P50406 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4499692 0.87 FPR2 (0.41) NPY1RNPY2R
SCHEMBL15968965 0.85 NPY1R (0.46) NPY1RNPY2RSLC6A4HTR6
SCHEMBL12598044 0.82 PDE4D (0.41)
SCHEMBL12598047 0.82 PDE4D (0.41)
SCHEMBL31096114 0.79 PDE4A (0.50) NPY1RNPY2RSLC6A4HTR6
SCHEMBL133005 0.79 PDE4A (0.50) NPY1RNPY2RSLC6A4HTR6
SCHEMBL19997590 0.78 NPY1R (0.50) NPY1RNPY2RSLC6A4HTR6
SCHEMBL265784 0.77 SLC6A4 (0.43) SLC6A4HTR6
SCHEMBL20833810 0.77 NPY1R (0.42) NPY1RNPY2RSLC6A4HTR6
SCHEMBL34469904 0.77 SLC6A4 (0.43) NPY1RNPY2RSLC6A4HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4227299-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) 2023-08-16 EP disclosed
WO-2022078152-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF 杭州中美华东制药有限公司 2022-04-21 WO disclosed