Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831947 | 0.77 | ALDH1A1 (0.46) | GAAKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL24329860 | 0.77 | NPM1 (0.43) | CDC7CDK2GAAKDM4EALDH1A1 | |
| SCHEMBL29449203 | 0.74 | PTPN1 (0.50) | CSNK1A1CLK2DYRK1ACLK4GAA | |
| SCHEMBL839531 | 0.74 | PTPN1 (0.50) | CSNK1A1CLK2DYRK1ACLK4GAA | |
| SCHEMBL3118498 | 0.71 | MAPT (0.55) | CDC7GAAKDM4EALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL834232 | 0.70 | MAPT (0.54) | CDC7GAAKDM4EALDH1A1RAB9A | |
| SCHEMBL22460800 | 0.70 | ALOX5AP (0.35) | KDM4EALDH1A1RAB9ASMN1; SMN2PTPN1 | |
| SCHEMBL830523 | 0.68 | KLK7 (0.43) | CSNK2A1GAAKDM4EALDH1A1RAB9A | |
| SCHEMBL112749 | 0.67 | ALDH1A1 (0.58) | DYRK1AKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL20587790 | 0.66 | ALDH1A1 (0.49) | GAAKDM4EALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078403-A1 | SUBSTITUTED PYRIDONE COMPOUND AND APPLICATION | 江苏先声药业有限公司 | 2022-04-21 | — | — | WO | disclosed |