Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24330494 | 0.89 | SOS1 (0.41) | KMT2ASOS1MAPTCCR6HKDC1 | |
| SCHEMBL30469366 | 0.89 | SOS1 (0.41) | KMT2ASOS1MAPTCCR6HKDC1 | |
| SCHEMBL29128003 | 0.87 | SOS1 (0.40) | KMT2ASOS1MAPTCCR6HKDC1 | |
| SCHEMBL24822480 | 0.87 | SOS1 (0.42) | KMT2ASOS1MAPTPKMCCR6 | |
| SCHEMBL12248176 | 0.84 | KMT2A (0.46) | KMT2ASOS1MAPTCCR6HKDC1 | |
| SCHEMBL709908 | 0.84 | SOS1 (0.47) | KMT2ASOS1MAPTNOTUMNPSR1 | |
| SCHEMBL14349262 | 0.82 | SOS1 (0.50) | KMT2ASOS1MAPTPKMNOTUM | |
| SCHEMBL30881269 | 0.82 | SOS1 (0.41) | KMT2ASOS1MAPTCCR6HKDC1 | |
| SCHEMBL16064425 | 0.82 | SOS1 (0.41) | KMT2ASOS1MAPTCCR6HKDC1 | |
| SCHEMBL16850327 | 0.82 | SOS1 (0.41) | KMT2ASOS1MAPTCCR6HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |