Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24330494 | 1.00 | SOS1 (0.41) | SOS1KMT2AMAPTCCR6HKDC1 | |
| SCHEMBL30881269 | 0.94 | SOS1 (0.41) | SOS1KMT2AMAPTCCR6HKDC1 | |
| SCHEMBL16064425 | 0.94 | SOS1 (0.41) | SOS1KMT2AMAPTCCR6HKDC1 | |
| SCHEMBL24330499 | 0.89 | KMT2A (0.43) | SOS1KMT2AMAPTCCR6HKDC1 | |
| SCHEMBL31024674 | 0.88 | ALDH1A1 (0.39) | SOS1MAPTLMNAALDH1A1DPP4 | |
| SCHEMBL25342892 | 0.88 | ALDH1A1 (0.39) | SOS1MAPTLMNAALDH1A1DPP4 | |
| SCHEMBL15795869 | 0.87 | SOS1 (0.41) | SOS1KMT2AMAPTCCR6HKDC1 | |
| SCHEMBL364111 | 0.87 | DPP4 (0.40) | SOS1MAPTLMNAALDH1A1DPP4 | |
| SCHEMBL29128003 | 0.86 | SOS1 (0.40) | SOS1KMT2AMAPTCCR6HKDC1 | |
| SCHEMBL709908 | 0.83 | SOS1 (0.47) | SOS1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940552-A | Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2023-10-24 | — | — | CN | disclosed |
| CN-116348464-A | Benzimidazolone GLP-1 receptor agonists and uses thereof | 杭州中美华东制药有限公司 | 2023-06-27 | — | — | CN | disclosed |