SCHEMBL2433367

SCHEMBL2433367

CC(C)(C)CC(C)(C)c1ccc2c(c1)[PH](=O)Oc1c-2cc(C(C)(C)CC(C)(C)C)cc1C(C)(C)CC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.33
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2437557 0.88 NPC1 (0.31) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL2431336 0.86 MAPK1 (0.43) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL2433368 0.83 CNR1 (0.40)
SCHEMBL2441681 0.78 NPC1 (0.37) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL30165004 0.78 NPC1 (0.37) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2436801 0.77 NPC1 (0.38) SHBGNPC1LMNAMAPK1CASP3
SCHEMBL2434927 0.73 MAPK1 (0.43) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL2431660 0.72 NPC1 (0.38) SHBGNPC1LMNAMAPK1CASP3
SCHEMBL2437559 0.71 CNR2 (0.39)
SCHEMBL2436810 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed