SCHEMBL2431336

SCHEMBL2431336

CCC(C)(C)c1ccc2c(c1)[PH](=O)Oc1c-2cc(C(C)(C)CC)cc1C(C)(C)CC

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
NPC1 O15118 1/20 0.43
LMNA P02545 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
ATM Q13315 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31
UBE2N P61088 2/20 0.31
GLA P06280 1/20 0.31
MITF O75030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2434927 0.87 MAPK1 (0.43) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL2433367 0.86 SHBG (0.33) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL2433368 0.84 CNR1 (0.40)
SCHEMBL2441681 0.79 NPC1 (0.37) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL30165004 0.79 NPC1 (0.37) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL2434428 0.76 NPC1 (0.51) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL2437557 0.73 NPC1 (0.31) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL2437559 0.72 CNR2 (0.39)
SCHEMBL2434135 0.71 NPC1 (0.51) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL2434274 0.70 NPC1 (0.34) MAPK1SMN1; SMN2NPC1LMNACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed
EP-0790262-B1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORP (JP) 2000-05-10 EP disclosed
US-6005034-A POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS CHISSO CORPOATION (JP) 1999-12-21 US disclosed
EP-0790262-A1 PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF CHISSO CORPORATION (JP) 1997-08-20 EP disclosed