Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.59 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045451 | 0.94 | TTR (0.63) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL25046377 | 0.88 | TTR (0.58) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL27016019 | 0.88 | TTR (0.64) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL23417940 | 0.87 | TTR (0.63) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL29468053 | 0.87 | TTR (0.62) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL23476626 | 0.87 | TTR (0.62) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL31542969 | 0.87 | TTR (0.64) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL31542972 | 0.87 | TTR (0.64) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL23417780 | 0.87 | TTR (0.64) | TTRFTONAALAD2RORCFOLH1 | |
| SCHEMBL25045455 | 0.85 | TTR (0.55) | TTRFTONAALAD2RORCFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079031-A1 | REACTIVE CONJUGATES | DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) | 2022-04-21 | — | — | WO | disclosed |