Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 7/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.52 |
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23417940 | 0.93 | TTR (0.63) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL26430106 | 0.91 | TTR (0.61) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL20809317 | 0.90 | FTO (0.70) | TTRFTONAALAD2NQO1KEAP1 | |
| SCHEMBL25045451 | 0.89 | TTR (0.63) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL31542969 | 0.89 | TTR (0.64) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL23417780 | 0.89 | TTR (0.64) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL31542972 | 0.89 | TTR (0.64) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL24335068 | 0.88 | TTR (0.62) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL15298976 | 0.87 | TTR (0.60) | TTRFTORORCNAALAD2NQO1 | |
| SCHEMBL18872864 | 0.87 | FTO (0.65) | TTRFTONAALAD2NQO1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016943-A1 | SYNTHETIC DNA BINDING DOMAINS AND USES THEREOF | THE UNIVERSITY OF CHICAGO (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016943-A1 | SYNTHETIC DNA BINDING DOMAINS AND USES THEREOF | CBFB, CNBP, BPTF | TTR 1998/4885FTO 4794/4885RORC 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.