⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Charcoal, Activated SCHEMBL10415937 | 1.00 | — | — | |
| Charcoal, Activated SCHEMBL338651 | 1.00 | — | — | |
| Charcoal, Activated SCHEMBL296208 | 0.87 | — | — | |
| Charcoal, Activated SCHEMBL729513 | 0.87 | — | — | |
| Fluoride SCHEMBL7885135 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL9722466 | 0.87 | — | — | |
| Charcoal, Activated SCHEMBL7914220 | 0.87 | — | — | |
| Charcoal, Activated SCHEMBL9068640 | 0.87 | — | — | |
| Charcoal, Activated SCHEMBL10623464 | 0.87 | — | — | |
| Charcoal, Activated SCHEMBL138810 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160237169-A1 | Binding Moieties Based On Shark IgNAR Domains | ADALTA LIMITED (AU) | 2016-08-18 | — | — | US | disclosed |
| EP-2330121-B1 | Binding moieties based on Shark IgNAR domains | ADALTA PTY LTD (AU) | 2014-09-03 | — | — | EP | disclosed |
| WO-2012137012-A1 | CRYSTAL STRUCTURE OF AN A2A ADENOSINE RECEPTOR | HEPTARES THERAPEUTICS LTD (GB) | 2012-10-11 | — | — | WO | disclosed |
| EP-1751181-B1 | BINDING MOIETIES BASED ON SHARK IgNAR DOMAINS | ADALTA PTY LTD (AU) | 2012-08-15 | — | — | EP | disclosed |
| US-20120003214-A1 | Binding Moieties Based On Shark IgNAR Domains | ADALTA PTY LTD (AU) | 2012-01-05 | — | — | US | disclosed |
| US-7977071-B2 | Binding moieties based on shark ignar domains | Adalta Pty Ltd. (AU) | 2011-07-12 | — | — | US | disclosed |
| EP-2330120-A2 | Binding moieties based on Shark IgNAR domains | AdAlta Pty Ltd (AU) | 2011-06-08 | — | — | EP | disclosed |
| EP-2330121-A2 | Binding moieties based on Shark IgNAR domains | AdAlta Pty Ltd (AU) | 2011-06-08 | — | — | EP | disclosed |
| US-20110112037-A1 | CRYSTAL STRUCTURE | Heptares Therapeutics Limited BioPark (GB) | 2011-05-12 | — | — | US | disclosed |
| WO-2011033322-A2 | CRYSTAL STRUCTURE | HEPTARES THERAPEUTICS LTD (GB) | 2011-03-24 | — | — | WO | disclosed |
| US-20050159901-A1 | Crystal structure of cytochrome P450 | ASTEX TECHNOLOGY LIMITED (GB) | 2005-07-21 | — | — | US | disclosed |
| EP-1554380-A1 | CRYSTAL STRUCTURE OF CYTOCHROME P450 3A4 AND ITS USE | Astex Technology Limited (GB) | 2005-07-20 | — | — | EP | disclosed |
| EP-1527170-A2 | CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME (BACE) MUTANTS AND USES THEREOF | Astex Technology Limited (GB) | 2005-05-04 | — | — | EP | disclosed |
| US-20050032119-A1 | Crystal structure of cytochrome P450 | ASTEX TECHNOLOGY LTD. (GB) | 2005-02-10 | — | — | US | disclosed |
| US-20040243319-A1 | Crystal structure of cytochrome P450 | ASTEX TECHNOLOGY LTD. (GB) | 2004-12-02 | — | — | US | disclosed |
| WO-2004096857-A2 | CRYSTALS OF CYTOCHROME P450 2C9, STRUCTURES THEREOF AND THEIR USE | ASTEX THERAPEUTICS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |
| US-20040096950-A1 | Crystal structure of beta site APP cleaving enzyme (BACE) and methods of use thereof | ASTEX THERAPEUTICS LIMITED (GB) | 2004-05-20 | — | — | US | disclosed |
| WO-2004038015-A1 | CRYSTAL STRUCTURE OF CYTOCHROME P450 3A4 AND ITS USE | ASTEX TECHNOLOGY LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |
| US-20040053383-A1 | Crystals of cytochrome P450 2C9, structures thereof and their use | ASTEX TECHNOLOGY LTD. (GB) | 2004-03-18 | — | — | US | disclosed |
| WO-2004011641-A2 | CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME (BACE) MUTANTS AND USES THEREOF | ASTEX TECHNOLOGY LIMITED (GB) | 2004-02-05 | — | — | WO | disclosed |