Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14932795 | 1.00 | CES2 (0.44) | CES2CES1HDAC8HDAC6EPHX1 | |
| SCHEMBL22947194 | 0.93 | — | — | |
| SCHEMBL11088056 | 0.88 | KMT2A (0.32) | SMN1; SMN2HSD17B10 | |
| SCHEMBL19540775 | 0.81 | CES2 (0.48) | CES2CES1HDAC8HDAC6EPHX1 | |
| SCHEMBL15199089 | 0.80 | EPHX1 (0.35) | EPHX1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15199088 | 0.80 | EPHX1 (0.35) | EPHX1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL21232394 | 0.78 | EPHX1 (0.42) | CES2CES1HDAC8HDAC6EPHX1 | |
| SCHEMBL1597093 | 0.78 | CES2 (0.41) | CES2CES1HDAC8HDAC6EPHX1 | |
| SCHEMBL29333109 | 0.78 | CES2 (0.55) | CES2CES1HDAC8HDAC6EPHX1 | |
| SCHEMBL28425729 | 0.78 | CES2 (0.55) | CES2CES1HDAC8HDAC6EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079445-A1 | BICYCLIC PEPTIDE LIGAND DRUG CONJUGATES | Bicyclerd Limited (GB) | 2022-04-21 | — | — | WO | disclosed |