Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.38 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174517 | 1.00 | TRPA1 (0.38) | TRPA1FERMT2ACACBCYP1A2CYP2C9 | |
| SCHEMBL30051661 | 0.82 | TRPA1 (0.38) | TRPA1FERMT2ACACBCYP1A2CYP2C9 | |
| SCHEMBL31207063 | 0.82 | PDE3B (0.42) | TRPA1FERMT2ACACBCYP1A2CYP2C9 | |
| SCHEMBL24338058 | 0.82 | PDE3B (0.42) | TRPA1FERMT2ACACBCYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL30050415 | 0.81 | TRPA1 (0.37) | TRPA1FERMT2ACACBCYP1A2CYP2C9 | |
| SCHEMBL18281239 | 0.76 | TRPA1 (0.40) | TRPA1FERMT2CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL242954 | 0.73 | PLAU (0.50) | HSD17B10CYP3A4CYP2C19CYP2A6LMNA | |
| SCHEMBL29526949 | 0.73 | PLAU (0.50) | HSD17B10CYP3A4CYP2C19CYP2A6LMNA | |
| SCHEMBL18425842 | 0.72 | SCN9A (0.35) | CYP1A2CYP2A6TDP1 | |
| SCHEMBL18425757 | 0.72 | ABL1 (0.35) | CYP1A2CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515956-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115515956-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |