Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | PRKCI | P41743 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435640 | 0.81 | TBXAS1 (0.54) | TBXAS1PRKCINAMPTIDO1BRD4 | |
| SCHEMBL19203784 | 0.79 | TBXAS1 (0.58) | TBXAS1PRKCINAMPTIDO1BRD4 | |
| SCHEMBL21037102 | 0.77 | TBXAS1 (0.50) | TBXAS1PRKCINAMPTIDO1RECQL | |
| SCHEMBL23686560 | 0.77 | TBXAS1 (0.50) | TBXAS1PRKCINAMPTIDO1BRD4 | |
| SCHEMBL10647788 | 0.76 | TBXAS1 (0.63) | TBXAS1PRKCINAMPT | |
| SCHEMBL26108096 | 0.75 | TBXAS1 (0.48) | TBXAS1NAMPT | |
| SCHEMBL10977942 | 0.74 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL12381495 | 0.72 | TBXAS1 (0.56) | TBXAS1CYP11B1CYP11B2NAMPTIDO1 | |
| SCHEMBL10974966 | 0.71 | TBXAS1 (0.67) | TBXAS1CYP11B1CYP11B2NAMPT | |
| SCHEMBL12093717 | 0.71 | TBXAS1 (0.43) | TBXAS1PRKCINAMPTIDO1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515956-A | Benzimidazole derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-12-23 | — | — | CN | disclosed |
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |