Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 13/20 | 0.48 |
| ▸ | CDK8 | P49336 | 13/20 | 0.48 |
| ▸ | CDK19 | Q9BWU1 | 13/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340345 | 0.76 | DUSP10 (0.43) | KDM4EALDH1A1LMNAMAPTDUSP10 | |
| SCHEMBL7248676 | 0.75 | CCNC (0.57) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL6986479 | 0.67 | KDM4E (0.52) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL18429258 | 0.66 | CCNC (1.00) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL7243276 | 0.66 | CCNC (0.61) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL7242796 | 0.65 | CCNC (0.80) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL6992723 | 0.65 | CCNC (0.49) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL6990354 | 0.64 | CCNC (0.64) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL6988781 | 0.64 | KDM4E (0.49) | CCNCCDK8CDK19KDM4EALDH1A1 | |
| SCHEMBL7249584 | 0.63 | DRD4 (0.45) | CCNCCDK8CDK19KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220098214-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING FIBROSIS | YALE UNIVERSITY | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098214-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING FIBROSIS | DUSP5, DUSP4, DUSP6 | CCNC 1020/4885CDK8 791/4885CDK19 2997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.