Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 16/20 | 0.61 |
| ▸ | CDK8 | P49336 | 16/20 | 0.61 |
| ▸ | CDK19 | Q9BWU1 | 16/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7248676 | 0.89 | CCNC (0.57) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL7249846 | 0.85 | CCNC (0.46) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL7246693 | 0.84 | DRD4 (0.67) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL7246971 | 0.83 | KDM4E (0.55) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL7241971 | 0.77 | DRD4 (0.45) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL7242734 | 0.76 | DRD4 (0.44) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL7248643 | 0.76 | DRD4 (0.44) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL7249584 | 0.75 | DRD4 (0.45) | CCNCCDK8CDK19CDK9DRD4 | |
| SCHEMBL18429198 | 0.73 | CCNC (1.00) | CCNCCDK8CDK19CDK9 | |
| SCHEMBL7246695 | 0.73 | CCNC (0.48) | CCNCCDK8CDK19CDK9DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158245-A1 | Fused heterocyclic derivatives, their production and use | TST, STS, AHR | CCNC 2012/4885CDK8 3614/4885CDK19 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.