Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.44 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CERT1 | Q9Y5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340370 | 1.00 | ASAH1 (0.58) | ASAH1EPHX2HDAC6ALDH1A1ACER2 | |
| SCHEMBL6346335 | 0.94 | EPHX2 (0.56) | ASAH1EPHX2FAAHP2RY10GPR174 | |
| SCHEMBL6346341 | 0.94 | EPHX2 (0.56) | ASAH1EPHX2FAAHP2RY10GPR174 | |
| SCHEMBL23373452 | 0.93 | ASAH1 (0.51) | ASAH1EPHX2HDAC6ALDH1A1MEN1 | |
| SCHEMBL28799819 | 0.86 | ASAH1 (0.47) | ASAH1EPHX2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL5415667 | 0.86 | ASAH1 (0.41) | ASAH1EPHX2HDAC6 | |
| SCHEMBL5415650 | 0.85 | ASAH1 (0.42) | ASAH1HDAC6CYP2C9 | |
| SCHEMBL7589241 | 0.85 | ASAH1 (0.52) | ASAH1EPHX2HDAC6FAAHMEN1 | |
| SCHEMBL24383281 | 0.85 | ALDH1A1 (0.44) | ASAH1HDAC6ALDH1A1MEN1KMT2A | |
| SCHEMBL10940345 | 0.84 | ASAH1 (0.51) | ASAH1EPHX2HDAC6FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322759-A | Phospholipid compounds and uses thereof | 吉利德科学公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022081973-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2022-04-21 | — | — | WO | disclosed |