Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19382439 | 0.79 | PKM (0.33) | ALDH1A1KDM4EKMT2AMEN1CYP2D6 | |
| SCHEMBL10269953 | 0.79 | KMT2A (0.46) | ALDH1A1KDM4EHSD17B10MAPK1KMT2A | |
| SCHEMBL880757 | 0.76 | KMT2A (0.45) | ALDH1A1MAPK1KMT2AMEN1CYP2D6 | |
| SCHEMBL12028780 | 0.76 | KMT2A (0.45) | ALDH1A1MAPK1KMT2AMEN1CYP2D6 | |
| SCHEMBL12345490 | 0.76 | KMT2A (0.45) | ALDH1A1MAPK1KMT2AMEN1CYP2D6 | |
| SCHEMBL14824990 | 0.75 | MEN1 (0.33) | KMT2AMEN1CYP2D6 | |
| SCHEMBL3118431 | 0.74 | — | — | |
| SCHEMBL22508030 | 0.73 | GAA (0.30) | GAAPKMTDP1 | |
| SCHEMBL24839930 | 0.72 | — | — | |
| SCHEMBL21547917 | 0.72 | KMT2A (0.41) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220073985-A1 | DISEASE STRATIFICATION OF LIVER DISEASE AND RELATED METHODS | SUPERFLUID DX, INC. | 2022-03-10 | — | — | US | disclosed |