Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340773 | 0.92 | HDAC3 (0.47) | SMN1; SMN2MAPTNPC1HDAC3HDAC1 | |
| SCHEMBL25837253 | 0.89 | HDAC3 (0.48) | SMN1; SMN2NPC1HDAC3HDAC1HDAC2 | |
| SCHEMBL25834809 | 0.81 | HDAC3 (0.42) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL25837258 | 0.80 | HDAC3 (0.45) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL24340807 | 0.79 | HDAC3 (0.56) | SMN1; SMN2MAPTNPC1ALDH1A1HDAC3 | |
| SCHEMBL26036543 | 0.78 | HDAC3 (0.47) | SMN1; SMN2MAPTNPC1ALDH1A1HDAC3 | |
| SCHEMBL26552016 | 0.77 | HPGD (0.42) | SMN1; SMN2MAPTNPC1ALDH1A1MAPK1 | |
| SCHEMBL25839793 | 0.77 | HDAC3 (0.49) | SMN1; SMN2MAPTNPC1ALDH1A1HDAC3 | |
| SCHEMBL25855949 | 0.76 | HDAC3 (0.53) | SMN1; SMN2NPC1HDAC3HDAC1HDAC2 | |
| SCHEMBL25851766 | 0.76 | HDAC3 (0.47) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056273-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |