SCHEMBL25837253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24340796	0.89	SMN1; SMN2 (0.48)	HDAC3SMN1; SMN2NPC1HDAC4HDAC1
	SCHEMBL24340773	0.89	HDAC3 (0.47)	HDAC3SMN1; SMN2NPC1RAB9AHDAC4
	SCHEMBL25855949	0.89	HDAC3 (0.53)	HDAC3HPGDSIRT2SIRT1POLB
	SCHEMBL25834809	0.82	HDAC3 (0.42)	HDAC3SMN1; SMN2RAB9AHDAC4HDAC1
	SCHEMBL25837258	0.82	HDAC3 (0.45)	HDAC3SMN1; SMN2HDAC4HDAC1HDAC7
	SCHEMBL25839637	0.80	HDAC3 (0.56)	HDAC3HPGDSIRT2SIRT1POLB
	SCHEMBL25851766	0.78	HDAC3 (0.47)	HDAC3SMN1; SMN2RAB9AHDAC4HDAC1
	SCHEMBL25856855	0.75	HDAC3 (0.52)	HDAC3HPGDSIRT2SIRT1POLB
	SCHEMBL25836957	0.72	HDAC3 (0.45)	HDAC3SMN1; SMN2RAB9AHDAC4HDAC1
	SCHEMBL24340635	0.71	HDAC3 (0.48)	HDAC3SMN1; SMN2HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.