Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455810 | 0.96 | KMT2A (0.61) | KMT2AMAPTFFAR4FFAR1LMNA | |
| SCHEMBL30966190 | 0.96 | KMT2A (0.61) | KMT2AMAPTFFAR4FFAR1LMNA | |
| SCHEMBL13890705 | 0.92 | KMT2A (0.53) | KMT2AMAPTFFAR4FFAR1CES2 | |
| SCHEMBL14536001 | 0.92 | KMT2A (0.57) | KMT2AMAPTFFAR4FFAR1CES2 | |
| SCHEMBL28626289 | 0.91 | MAPT (0.56) | KMT2AMAPTFFAR4FFAR1LMNA | |
| SCHEMBL29190270 | 0.90 | KMT2A (0.55) | KMT2AMAPTFFAR4FFAR1LMNA | |
| SCHEMBL19085418 | 0.88 | CA2 (0.61) | KMT2AMAPTCES2CES1HAO1 | |
| SCHEMBL30966169 | 0.88 | ACE2 (0.56) | KMT2AMAPTFFAR4FFAR1LMNA | |
| SCHEMBL30966171 | 0.88 | ACE2 (0.56) | KMT2AMAPTFFAR4FFAR1LMNA | |
| SCHEMBL30966162 | 0.88 | KMT2A (0.53) | KMT2AMAPTFFAR4FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081544-A1 | IMPROVED PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES | TRANSLATE BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |