Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.40 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24343347 | 0.96 | CYP1A2 (0.46) | CYP1A2ALDH1A1NPSR1SLC2A1TDP1 | |
| SCHEMBL24344666 | 0.94 | MEN1 (0.41) | CYP1A2ALDH1A1NPSR1SLC2A1TDP1 | |
| SCHEMBL24344658 | 0.90 | MEN1 (0.43) | CYP1A2ALDH1A1NPSR1TDP1MAPT | |
| SCHEMBL31150589 | 0.89 | SLC2A1 (0.42) | CYP1A2SLC2A1MAPTSLC2A4SLC2A8 | |
| SCHEMBL24343955 | 0.89 | SLC2A1 (0.42) | CYP1A2SLC2A1MAPTSLC2A4SLC2A8 | |
| SCHEMBL24343530 | 0.86 | SLC2A1 (0.41) | ALDH1A1SLC2A1MEN1KMT2AGAA | |
| SCHEMBL24343509 | 0.85 | HSD17B2 (0.45) | CYP1A2SLC2A1MAPTSLC2A4SLC2A8 | |
| SCHEMBL31150696 | 0.85 | HSD17B2 (0.45) | CYP1A2SLC2A1MAPTSLC2A4SLC2A8 | |
| SCHEMBL24343489 | 0.84 | TSHR (0.42) | ALDH1A1NPSR1SLC2A1TDP1MEN1 | |
| SCHEMBL24343315 | 0.84 | SLC2A1 (0.44) | ALDH1A1NPSR1SLC2A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12109263-B2 | Integrin agonists or activating compounds and methods for making and using same | 7 HILLS PHARMA INC. | 2024-10-08 | — | — | US | claimed |
| US-20220118086-A1 | INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME | 7 Hills Pharma LLC (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118086-A1 | INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME | ICOS, CD47, CD274 | CYP1A2 3558/4885ALDH1A1 398/4885NPSR1 1263/4885 |
| US-12109263-B2 | Integrin agonists or activating compounds and methods for making and using same | ICOS, CD47, CD274 | CYP1A2 3558/4885ALDH1A1 398/4885NPSR1 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.