SCHEMBL24344666

SCHEMBL24344666

COc1ccc(CN(Cc2ccc(N(C)C)cc2)C(=O)OCCOCCOC(=O)c2cccc(C(=O)OCCOCCOC(=O)N(Cc3ccc(OC)cc3)Cc3ccc(N(C)C)cc3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GAA P10253 3/20 0.41
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SLC2A1 P11166 2/20 0.38
CYP1A2 P05177 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 4/20 0.37
TDP1 Q9NUW8 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 2/20 0.37
ESR2 Q92731 1/20 0.37
NOX1 Q9Y5S8 1/20 0.37
ACHE P22303 1/20 0.37
USP2 O75604 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24344658 0.97 MEN1 (0.43) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL24344654 0.94 CYP1A2 (0.43) MEN1KMT2AGAAALDH1A1SLC2A1
SCHEMBL24343530 0.92 SLC2A1 (0.41) MEN1KMT2AGAAALDH1A1SLC2A1
SCHEMBL24343347 0.90 CYP1A2 (0.46) MEN1KMT2AGAAALDH1A1SLC2A1
SCHEMBL31150686 0.89 SLC2A1 (0.42) MEN1KMT2AGAAALDH1A1SLC2A1
SCHEMBL24343528 0.89 SLC2A1 (0.42) MEN1KMT2AGAAALDH1A1SLC2A1
SCHEMBL26619039 0.89 MEN1 (0.42) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL26619114 0.89 MEN1 (0.43) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL24343923 0.86 MEN1 (0.41) MEN1KMT2AGAAALDH1A1LMNA
SCHEMBL24343490 0.86 MEN1 (0.41) MEN1KMT2AGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4518842-A1 NOVEL LIPID-BASED SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS CARRIER COMPOSITIONS, INTEGRIN AGONIST ADJUVANT PHARMACEUTICAL COMPOSITIONS THEREFROM, AND METHODS FOR MAKING AND USING SAME 7 Hills Pharma Inc. (US) 2025-03-12 EP disclosed
US-20230372253-A1 NOVEL LIPID-BASED SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS CARRIER COMPOSITIONS, INTEGRIN AGONIST ADJUVANT PHARMACEUTICAL COMPOSITIONS THEREFROM, AND METHODS FOR MAKING AND USING SAME 7 Hills Pharma LLC (US) 2023-11-23 US disclosed
WO-2023215314-A1 NOVEL LIPID-BASED SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS CARRIER COMPOSITIONS, INTEGRIN AGONIST ADJUVANT PHARMACEUTICAL COMPOSITIONS THEREFROM, AND METHODS FOR MAKING AND USING SAME 7 Hills Pharma LLC (US) 2023-11-09 WO disclosed
US-20220118086-A1 INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME 7 Hills Pharma LLC (US) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220118086-A1 INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME ICOS, CD47, CD274 MEN1 2690/4885KMT2A 1028/4885GAA 1386/4885
US-20230372253-A1 NOVEL LIPID-BASED SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS CARRIER COMPOSITIONS, INTEGRIN AGONIST ADJUVANT PHARMACEUTICAL COMPOSITIONS THEREFROM, AND METHODS FOR MAKING AND USING SAME ITGAM, ITGA2, ADGRF1 MEN1 4764/4885KMT2A 3796/4885GAA 4197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.