Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303998 | 0.87 | REN (0.74) | REN | |
| SCHEMBL7296609 | 0.87 | REN (0.74) | REN | |
| SCHEMBL457940 | 0.83 | REN (0.67) | REN | |
| SCHEMBL2434475 | 0.79 | REN (0.58) | REN | |
| SCHEMBL15210023 | 0.78 | REN (0.83) | REN | |
| Aliskiren SCHEMBL455490 | 0.77 | REN (1.00) | REN | |
| Aliskiren SCHEMBL3476535 | 0.77 | REN (1.00) | REN | |
| Aliskiren SCHEMBL3476537 | 0.77 | REN (1.00) | REN | |
| Aliskiren SCHEMBL7965529 | 0.77 | REN (1.00) | REN | |
| Aliskiren SCHEMBL13351616 | 0.77 | REN (1.00) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364292-A2 | AMIDE INHIBITORS OF RENIN | Auspex Pharmaceuticals, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010059967-A2 | AMIDE INHIBITORS OF RENIN | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |