Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.32 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29534401 | 0.81 | DRD1 (0.40) | — | |
| SCHEMBL24343780 | 0.81 | DRD1 (0.40) | — | |
| SCHEMBL29534616 | 0.81 | AMY1A (0.36) | CYP19A1NQO2 | |
| SCHEMBL24343762 | 0.81 | AMY1A (0.36) | CYP19A1NQO2 | |
| SCHEMBL24344849 | 0.79 | PDE10A (0.35) | BRD9BRD7DHFR | |
| SCHEMBL24343823 | 0.76 | HSP90AA1 (0.43) | — | |
| SCHEMBL29534658 | 0.76 | HSP90AA1 (0.43) | — | |
| SCHEMBL24344404 | 0.76 | ABL1 (0.40) | QRFPR | |
| SCHEMBL24344401 | 0.76 | AR (0.43) | — | |
| SCHEMBL29534526 | 0.76 | ABL1 (0.40) | QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076975-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |