Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457599 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL3201532 | 0.91 | KDM4E (0.55) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL16981203 | 0.86 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL10458204 | 0.84 | KDM4E (0.52) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL18704576 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL2617363 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL8794130 | 0.81 | TP53 (0.64) | ALDH1A1LMNATDP1SMN1; SMN2HPGD | |
| SCHEMBL2000918 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL11443005 | 0.81 | MAPK1 (0.52) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL11649440 | 0.80 | CSNK2A1 (0.60) | KDM4EALDH1A1LMNATDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981773-A1 | DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION | Technische Universität Berlin (DE) | 2022-04-13 | — | — | EP | disclosed |
| EP-3981773-A1 | DYNAMIC KINETIC RESOLUTION OF ALCOHOLS BY ENANTIOSELECTIVE SILYLATION | Technische Universität Berlin (DE) | 2022-04-13 | — | — | EP | disclosed |