Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPGM | P07738 | 6/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26705913 | 0.94 | BPGM (0.46) | BPGMACACBGHSRMAP3K5 | |
| SCHEMBL24349410 | 0.92 | BPGM (0.44) | BPGMACACBMAP3K5 | |
| SCHEMBL24348045 | 0.87 | BPGM (0.47) | BPGMMAP3K5 | |
| SCHEMBL24348425 | 0.87 | BPGM (0.48) | BPGMMAP3K5 | |
| SCHEMBL24349248 | 0.85 | BPGM (0.46) | BPGMGHSRMAP3K5 | |
| SCHEMBL24348462 | 0.84 | BPGM (0.45) | BPGMMAP3K5 | |
| SCHEMBL24348391 | 0.84 | BPGM (0.44) | BPGM | |
| SCHEMBL24348468 | 0.83 | BPGM (0.44) | BPGM | |
| SCHEMBL26704394 | 0.82 | BPGM (0.57) | BPGM | |
| SCHEMBL24349003 | 0.81 | BPGM (0.51) | BPGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056449-A1 | COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION (US) | 2022-03-17 | — | — | WO | disclosed |