Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453427 | 0.81 | CYP2D6 (0.46) | LTA4HCYP2D6CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL9168621 | 0.79 | RARB (0.47) | NR5A1RARBLTA4HTP53TSHR | |
| SCHEMBL27483624 | 0.79 | LTA4H (0.64) | NR5A1RARBLTA4HTP53TSHR | |
| Hydrogen Sulfide SCHEMBL27796580 | 0.77 | LTA4H (0.62) | NR5A1RARBLTA4HTP53TSHR | |
| Phosphine SCHEMBL27457623 | 0.77 | LTA4H (0.62) | NR5A1RARBLTA4HTP53TSHR | |
| SCHEMBL31550426 | 0.77 | LTA4H (0.66) | NR5A1RARBLTA4HTP53TSHR | |
| SCHEMBL435380 | 0.77 | LTA4H (0.53) | NR5A1RARBLTA4HTP53TSHR | |
| SCHEMBL2877838 | 0.77 | LTA4H (0.53) | NR5A1RARBLTA4HTP53TSHR | |
| SCHEMBL28141538 | 0.76 | LTA4H (0.56) | NR5A1RARBLTA4HTP53TSHR | |
| SCHEMBL28142366 | 0.76 | LTA4H (0.56) | NR5A1RARBLTA4HTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078028-B1 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA (US) | 2011-09-07 | — | — | EP | disclosed |
| EP-2078028-A1 | PHOTOACTIVE COMPOUNDS | AZ Electronic Materials USA Corp. (US) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008041123-A1 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2008-04-10 | — | — | WO | disclosed |