Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609560 | 0.84 | SSTR4 (0.48) | SSTR4NPSR1IRAK4FLT3NPC1 | |
| SCHEMBL24348667 | 0.83 | SSTR4 (0.44) | SSTR4NPSR1IRAK4FLT3ALDH1A1 | |
| SCHEMBL9537296 | 0.81 | SSTR4 (0.46) | SSTR4NPSR1IRAK4FLT3NPC1 | |
| SCHEMBL27221248 | 0.81 | SSTR4 (0.49) | SSTR4NPSR1FLT3NPC1ALDH1A1 | |
| SCHEMBL21554029 | 0.79 | SSTR4 (0.46) | SSTR4NPSR1IRAK4FLT3NPC1 | |
| SCHEMBL12463958 | 0.78 | SSTR4 (0.44) | SSTR4NPSR1IRAK4FLT3NPC1 | |
| SCHEMBL24348668 | 0.76 | GGPS1 (0.46) | SSTR4NPSR1FLT3NPC1ALDH1A1 | |
| SCHEMBL24348662 | 0.76 | SSTR4 (0.43) | SSTR4NPSR1IRAK4FLT3ADORA3 | |
| SCHEMBL20439080 | 0.76 | SSTR4 (0.45) | SSTR4NPSR1IRAK4FLT3NPC1 | |
| SCHEMBL24348738 | 0.74 | SSTR4 (0.80) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058745-A9 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022058745-A2 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-03-24 | — | — | WO | disclosed |