Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564894 | 0.89 | MAP2K1 (0.43) | CLK1MAP2K2MAP2K1FLT1MKNK1 | |
| SCHEMBL24350196 | 0.86 | ATM (0.44) | KDM4EATMCLK1CSF1RNPC1 | |
| SCHEMBL24349947 | 0.85 | CISD2 (0.40) | KDM4ECISD2SYKCSF1RLMNA | |
| SCHEMBL24349945 | 0.85 | ATM (0.43) | KDM4EATMCLK1CSF1RNPC1 | |
| SCHEMBL24349922 | 0.83 | CISD2 (0.40) | CISD2SYKCSF1RMAPTMAP2K2 | |
| SCHEMBL24349753 | 0.79 | MAP2K1 (0.47) | MAP2K2MAP2K1 | |
| SCHEMBL29302059 | 0.79 | KDM4E (0.41) | KDM4ECISD2SYKCSF1RCOMT | |
| SCHEMBL4109917 | 0.79 | MAP2K1 (0.45) | KDM4ECLK1TP53LMNACYP1A2 | |
| SCHEMBL4109923 | 0.78 | MAP2K1 (0.56) | KDM4ECLK1NPC1RAB9ALMNA | |
| SCHEMBL4127775 | 0.78 | CLK1 (0.50) | KDM4EATMCLK1TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4233834-A2 | ARYL-ANILINE AND HETEROARYL-ANILINE COMPOUNDS FOR TREATMENT OF BIRTHMARKS | NFlection Therapeutics, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3624795-B1 | FUSED HETEROAROMATIC-ANILINE COMPOUNDS FOR TREATMENT OF DERMAL DISORDERS | NFLECTION THERAPEUTICS INC (US) | 2022-04-20 | — | — | EP | disclosed |