SCHEMBL2435401

SCHEMBL2435401

C1CCN(C2CCOCC2)C1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
MBTD1 Q05BQ5 1/20 0.43
HRH3 Q9Y5N1 11/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13207 0.97 L3MBTL3 (0.46) L3MBTL3L3MBTL1MBTD1HRH3KDM4E
SCHEMBL6464543 0.94 HRH3 (0.46) L3MBTL3L3MBTL1MBTD1HRH3KDM4E
SCHEMBL14528417 0.93 L3MBTL3 (0.43) L3MBTL3L3MBTL1MBTD1HRH3KDM4E
SCHEMBL14907095 0.91 L3MBTL3 (0.49) L3MBTL3L3MBTL1HRH3KDM4EALDH1A1
SCHEMBL25672747 0.89 L3MBTL3 (0.47) L3MBTL3L3MBTL1HRH3KDM4EALDH1A1
SCHEMBL5004073 0.89 HRH3 (0.41) L3MBTL3L3MBTL1MBTD1HRH3KDM4E
SCHEMBL16877337 0.87 L3MBTL3 (0.43) L3MBTL3L3MBTL1MBTD1HRH3KDM4E
SCHEMBL18207732 0.87 SMN1; SMN2 (0.48) L3MBTL3L3MBTL1HRH3KDM4EALDH1A1
SCHEMBL14862483 0.86 SMN1; SMN2 (0.50) L3MBTL3L3MBTL1HRH3ALDH1A1HPGD
SCHEMBL14529673 0.84 KDM2B (0.36) L3MBTL3L3MBTL1HRH3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-11-24 US claimed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
CN-117736199-A 6H-dibenzo [ b, d ] pyran derivative substituted by 3-position oxygen-containing group, and preparation method and application thereof 西安交通大学 2024-03-22 CN disclosed
US-11369599-B2 Melt-extruded solid dispersions containing an apoptosis-inducing agent ABBVIE INC. (US) 2022-06-28 US disclosed
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-07-29 US disclosed
EP-2986616-B1 TRICYCLIC TRIAZOLIC COMPOUNDS AS SIGMA RECEPTORS LIGANS ESTEVE LABOR DR (ES) 2017-03-29 EP disclosed
EP-2499146-B1 TRICYCLIC PYRAZOL AMINE DERIVATIVES MERCK SERONO SA (CH) 2016-09-21 EP disclosed
EP-2794608-B1 TETRAAZA-CYCLOPENTA[A]INDENYL AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS MERCK PATENT GMBH (DE) 2016-09-14 EP disclosed
EP-2435433-B1 (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES AS FSH RECEPTOR AGONISTS FOR THE TREATMENT OF FERTILITY DISORDERS MERCK SHARP & DOHME (NL) 2013-08-28 EP disclosed
EP-2109605-B1 2- [(PHENYLAMINO) -PYRIMIDIN-4YLAMIN0] -CYCLOPENTANE CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF KINASES OF THE CELL CYCLE FOR THE TREATMENT OF CANCER BOEHRINGER INGELHEIM INT (DE) 2013-02-20 EP disclosed
US-20120238545-A1 TRICYCLIC PYRAZOL AMINE DERIVATIVES MERCK SERONO SA (CH) 2012-09-20 US disclosed
US-8071587-B2 (Dihydro)imidazoiso[5,1-A]quinolines N. V. ORGANON (NL) 2011-12-06 US disclosed
WO-2011120025-A1 INDAZOLYL-PYRIMIDINES AS KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2011-09-29 WO disclosed
WO-2011095434-A1 TETRAHYDRO-PYRAN DERIVATIVES AGAINST NEUROLOGICAL ILLNESSES F. HOFFMANN-LA ROCHE AG (CH) 2011-08-11 WO disclosed
US-20100324021-A1 (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES N.V. ORGANON (NL) 2010-12-23 US disclosed
WO-2010136438-A1 (DIHYDRO) IMIDAZOISO (5, 1-A) QUINOLINES AS FSH RECEPTOR AGONISTS FOR THE TREATMENT OF FERTILITY DISORDERS N.V. ORGANON (NL) 2010-12-02 WO disclosed
US-20090163465-A1 Pyrimidines as PLK inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-25 US disclosed
US-20090149438-A1 Pyrimidines as PLK inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-06-11 US disclosed
WO-2007053498-A1 COMPOUNDS USEFUL AS ANTAGONISTS OF CCR2 MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-05-10 WO disclosed
EP-0997474-B1 Antithrombotic agents PFIZER (US) 2003-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 L3MBTL3 114/4885L3MBTL1 218/4885MBTD1 2066/4885
US-20120238545-A1 TRICYCLIC PYRAZOL AMINE DERIVATIVES PI4KB, MTOR, PI4KA L3MBTL3 4599/4885L3MBTL1 4614/4885MBTD1 3743/4885
US-20100324021-A1 (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES NQO2, IPO5, SCN5A L3MBTL3 4055/4885L3MBTL1 3294/4885MBTD1 3157/4885
US-20090163465-A1 Pyrimidines as PLK inhibitors PLK2, PLK3, TYMP L3MBTL3 1217/4885L3MBTL1 849/4885MBTD1 3133/4885
US-11369599-B2 Melt-extruded solid dispersions containing an apoptosis-inducing agent BCL2, BAX, BCL2L1 L3MBTL3 1812/4885L3MBTL1 1172/4885MBTD1 354/4885
US-20090149438-A1 Pyrimidines as PLK inhibitors PLK2, PLK3, TYMP L3MBTL3 1217/4885L3MBTL1 849/4885MBTD1 3133/4885
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ZFX, F13B, GRN L3MBTL3 1368/4885L3MBTL1 718/4885MBTD1 2460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.