Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24355252 | 1.00 | MAPT (0.38) | MAPTMEN1KMT2AGRM8GRM7 | |
| SCHEMBL15018764 | 0.78 | ESR1 (0.44) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL1162469 | 0.76 | TSHR (0.53) | CYP3A4ALOX15HIF1AHSD17B10TSHR | |
| SCHEMBL2356074 | 0.76 | CYP2A6 (0.42) | MEN1KMT2AALDH1A1CYP3A4TSHR | |
| SCHEMBL15833075 | 0.76 | HDAC3 (0.42) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6404428 | 0.76 | MAPT (0.38) | MAPTMEN1KMT2AGRM8GRM7 | |
| SCHEMBL1712779 | 0.76 | HDAC3 (0.42) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28839965 | 0.76 | CYP1A2 (0.42) | MEN1KMT2AALOX15SMN1; SMN2CNR1 | |
| SCHEMBL21436893 | 0.76 | CYP1A2 (0.42) | MEN1KMT2AALOX15SMN1; SMN2CNR1 | |
| SCHEMBL3793092 | 0.76 | TPMT (0.36) | ALOX15TSHRAPEX1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127297-A1 | Novel Antibacterial 3\"-Derivatives Of 4,6-Disubstituted 2,5-Dideoxystreptamine Aminoglycoside Antibiotics | AGILEBIOTICS B.V. (NL) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127297-A1 | Novel Antibacterial 3\"-Derivatives Of 4,6-Disubstituted 2,5-Dideoxystreptamine Aminoglycoside Antibiotics | ABCC1, AMPD3, MRPS35 | MAPT 3033/4885MEN1 4383/4885KMT2A 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.