Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MASP2 | O00187 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646387 | 0.81 | TYR (0.43) | HRH3ALDH1A1HIF1AMAPK1SMN1; SMN2 | |
| SCHEMBL387119 | 0.78 | ESR1 (0.44) | MAPTMEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL3885072 | 0.76 | ORAI1 (0.42) | HRH3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4905102 | 0.76 | ORAI1 (0.42) | MAPTMEN1KMT2AHRH3ALDH1A1 | |
| SCHEMBL10684990 | 0.76 | HRH3 (0.38) | HRH3 | |
| SCHEMBL24355252 | 0.76 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL24355247 | 0.76 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL12015736 | 0.76 | TSHR (0.48) | HRH3ALOX15HIF1ATDP1CYP19A1 | |
| SCHEMBL9739296 | 0.76 | CYP2C19 (0.46) | MAPTMEN1KMT2AHRH3CYP3A4 | |
| SCHEMBL3893413 | 0.75 | TSHR (0.43) | ALDH1A1HIF1AMAPK1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6279390-A | — | — | None | — | — | JP | disclosed |
| US-6858626-B2 | Enzyme inhibitor; antiinflammatory agents; osteoporosis | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030139597-A1 | Novel Cyclic hydroxamic acid as metalloproteinase inhibitors | XUE CHU-BIAO (US) | 2003-07-24 | — | — | US | disclosed |
| US-6429213-B1 | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIS AGENTS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-08-06 | — | — | US | disclosed |
| US-5811398-A | Platelet aggregation inhibitors containing C-terminal aminergic side chain amino acid residues | G. D. SEARLE & CO. (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0835265-A1 | PLATELET AGGREGATION INHIBITORS CONTAINING C-TERMINAL AMINERGIC SIDE CHAIN AMINO ACID RESIDUES | G.D. SEARLE & CO. (US) | 1998-04-15 | — | — | EP | disclosed |
| WO-1996032415-A1 | PLATELET AGGREGATION INHIBITORS CONTAINING C-TERMINAL AMINERGIC SIDE CHAIN AMINO ACID RESIDUES | G.D. SEARLE & CO. (US) | 1996-10-17 | — | — | WO | disclosed |
| JP-H06279390-A | TRIAMINE, TRIISOCYANATE AND PRODUCTION THEREOF | MITSUI TOATSU CHEM INC | 1994-10-04 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139597-A1 | Novel Cyclic hydroxamic acid as metalloproteinase inhibitors | MMP9, MMP2, MMP25 | MAPT 4850/4885MEN1 3733/4885KMT2A 885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.