Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22081840 | 1.00 | THRB (0.38) | THRBMEN1KMT2AF2 | |
| SCHEMBL19490963 | 0.74 | THRB (0.38) | THRBMEN1KMT2A | |
| SCHEMBL19490967 | 0.74 | THRB (0.38) | THRBMEN1KMT2A | |
| SCHEMBL13701168 | 0.73 | F2 (0.42) | F2 | |
| SCHEMBL3675184 | 0.70 | THRB (0.43) | THRBMEN1KMT2A | |
| SCHEMBL14609198 | 0.70 | THRB (0.30) | THRBMEN1KMT2A | |
| SCHEMBL22081096 | 0.70 | EPHX1 (0.40) | THRBMEN1KMT2A | |
| SCHEMBL7524414 | 0.69 | — | — | |
| SCHEMBL24355135 | 0.68 | THRB (0.36) | THRBMEN1KMT2A | |
| SCHEMBL20877624 | 0.67 | F2 (0.36) | THRBMEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127297-A1 | Novel Antibacterial 3\"-Derivatives Of 4,6-Disubstituted 2,5-Dideoxystreptamine Aminoglycoside Antibiotics | AGILEBIOTICS B.V. (NL) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127297-A1 | Novel Antibacterial 3\"-Derivatives Of 4,6-Disubstituted 2,5-Dideoxystreptamine Aminoglycoside Antibiotics | ABCC1, AMPD3, MRPS35 | THRB 3882/4885MEN1 4383/4885KMT2A 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.