Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2381338 | 0.81 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL24358021 | 0.75 | MEN1 (0.52) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL29601739 | 0.75 | MEN1 (0.52) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL30745730 | 0.74 | NPC1 (0.57) | MEN1KMT2AALDH1A1HSD17B10MAPT | |
| SCHEMBL27039641 | 0.74 | MEN1 (0.55) | MEN1KMT2AALDH1A1TP53MAPT | |
| SCHEMBL24358194 | 0.74 | NPC1 (0.57) | MEN1KMT2AALDH1A1HSD17B10MAPT | |
| SCHEMBL30745797 | 0.74 | MEN1 (0.55) | MEN1KMT2AALDH1A1TP53MAPT | |
| SCHEMBL24358034 | 0.72 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL7403707 | 0.71 | RAB9A (0.68) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL27916462 | 0.70 | MAPT (0.45) | MEN1KMT2AL3MBTL1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |