Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 7/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PTPRA | P18433 | 1/20 | 0.58 |
| ▸ | PTPRB | P23467 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CTRC | Q99895 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358519 | 0.93 | MPL (0.65) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL21686432 | 0.89 | CYP1A2 (0.68) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL21686458 | 0.87 | MPL (0.59) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL21686435 | 0.82 | NSD2 (0.56) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL31498510 | 0.80 | MAPK1 (0.83) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL24358518 | 0.80 | MPL (0.67) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL4532471 | 0.79 | MPL (0.71) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL31183028 | 0.79 | MPL (0.71) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL4532468 | 0.79 | MPL (0.71) | MPLCYP1A2CYP2C9HIF1ATSHR | |
| SCHEMBL1807925 | 0.78 | MPL (0.51) | MPLCYP1A2CTRCMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362518-B1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | THE UWM RES FOUNDATION INC (US) | 2022-04-27 | — | — | EP | disclosed |