SCHEMBL4532471

SCHEMBL4532471

O=S(=O)(O)c1ccccc1N=Nc1c(O)ccc2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 7/20 0.71
CTRC Q99895 2/20 0.71
CYP1A2 P05177 3/20 0.69
HIF1A Q16665 2/20 0.69
CYP2C9 P11712 2/20 0.69
TSHR P16473 1/20 0.69
PTPRA P18433 1/20 0.69
PTPRB P23467 1/20 0.69
CYP2C19 P33261 1/20 0.69
RAPGEF4 Q8WZA2 1/20 0.69
HSD17B10 Q99714 1/20 0.69
MAPK1 P28482 4/20 0.61
ALDH1A1 P00352 2/20 0.61
MAPT P10636 4/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
KDM4E B2RXH2 1/20 0.61
NPC1 O15118 1/20 0.61
KMT2A Q03164 3/20 0.59
GAA P10253 2/20 0.59
TDP1 Q9NUW8 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31183028 1.00 MPL (0.71) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL4532468 1.00 MPL (0.71) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL21686432 0.91 CYP1A2 (0.68) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL10621000 0.89 CYP1A2 (0.70) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL10621005 0.89 CYP1A2 (0.70) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL943732 0.87 MPL (0.76) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL933792 0.87 CYP1A2 (0.78) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL933793 0.87 CYP1A2 (0.78) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL5701120 0.86 CTRB1 (0.73) MPLCTRCCYP1A2HIF1ACYP2C9
SCHEMBL30049470 0.86 CTRB1 (0.73) MPLCTRCCYP1A2HIF1ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7611824-B2 Dummy plate precursor for planographic printing and method for producing printed plate and dummy plate FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-20050153221-A1 Dummy plate precursor for planographic printing and method for producing printed plate and dummy plate FUJI PHOTO FILM CO., LTD. 2005-07-14 US disclosed