Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.80 |
| ▸ | PGR | P06401 | 6/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MLNR | O43193 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358688 | 1.00 | AR (0.80) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL24358698 | 1.00 | AR (0.80) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL24358738 | 1.00 | AR (0.80) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL24358686 | 1.00 | AR (0.80) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL24358732 | 0.95 | AR (0.83) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL1591638 | 0.95 | AR (0.83) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL24358816 | 0.95 | AR (0.83) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL835740 | 0.93 | AR (0.68) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL9622215 | 0.93 | AR (0.68) | ARPGRCHRM1LMNANR3C1 | |
| SCHEMBL25473350 | 0.91 | AR (0.77) | ARPGRCHRM1LMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018181-A1 | PROCESS FOR THE PRODUCTION OF 21-(ACETYLOXY)-17-(PROPIONYLOXY)-PREGN-4-ENE-3,20-DIONE | INDUSTRIALE CHIMICA S.R.L. (IT) | 2024-01-18 | — | — | US | disclosed |
| US-20240018181-A1 | PROCESS FOR THE PRODUCTION OF 21-(ACETYLOXY)-17-(PROPIONYLOXY)-PREGN-4-ENE-3,20-DIONE | INDUSTRIALE CHIMICA S.R.L. (IT) | 2024-01-18 | — | — | US | disclosed |
| WO-2022084752-A1 | PROCESS FOR THE PRODUCTION OF 21-(ACETYLOXY)-17-(PROPIONYLOXY)-PREGN-4-ENE-3,20-DIONE | INDUSTRIALE CHIMICA S.R.L. (IT) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018181-A1 | PROCESS FOR THE PRODUCTION OF 21-(ACETYLOXY)-17-(PROPIONYLOXY)-PREGN-4-ENE-3,20-DIONE | CYP17A1, HSD17B11, HSD17B7 | AR 111/4885PGR 66/4885CHRM1 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.