Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 3/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512778 | 0.86 | HTR2C (0.68) | KDM4EHPGDALDH1A1HTR2CIGF1R | |
| SCHEMBL15780901 | 0.75 | ALDH1A1 (0.46) | KDM4EHPGDALDH1A1IGF1RCYP1A2 | |
| SCHEMBL11278582 | 0.75 | HTR2C (0.58) | KDM4EHPGDALDH1A1HTR2CGBA1 | |
| SCHEMBL15246924 | 0.73 | ALDH1A1 (0.52) | KDM4EHPGDALDH1A1GBA1CYP1A2 | |
| SCHEMBL11286794 | 0.71 | HTR2C (0.62) | KDM4EHPGDALDH1A1HTR2CGBA1 | |
| SCHEMBL13153128 | 0.71 | KDM4E (0.63) | KDM4EHPGDALDH1A1ACHEKMT2A | |
| SCHEMBL24697999 | 0.70 | KDM4E (0.49) | KDM4EHPGDALDH1A1HTR2CIGF1R | |
| SCHEMBL1707790 | 0.70 | ALDH1A1 (0.49) | KDM4EHPGDALDH1A1CYP1A2HTT | |
| SCHEMBL18568567 | 0.70 | KDM4E (0.61) | KDM4EHPGDALDH1A1ACHEBCHE | |
| SCHEMBL15207587 | 0.70 | HRH1 (0.50) | KDM4EHPGDALDH1A1CYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |