Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416125 | 0.82 | ELANE (0.55) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL16397249 | 0.81 | ELANE (0.53) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL9179469 | 0.80 | ALDH1A1 (0.53) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL2257976 | 0.79 | ELANE (0.61) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL16714701 | 0.79 | ELANE (0.51) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL7932603 | 0.77 | ELANE (0.57) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL24126788 | 0.76 | ELANE (0.56) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL9634937 | 0.76 | ELANE (0.47) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL9824381 | 0.76 | ELANE (0.57) | ELANEF2PLGCTSGCMA1 | |
| SCHEMBL4002014 | 0.75 | ELANE (0.53) | ELANEF2PLGCTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |