Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 20/20 | 0.52 |
| ▸ | TAF1 | P21675 | 18/20 | 0.52 |
| ▸ | BRD9 | Q9H8M2 | 18/20 | 0.52 |
| ▸ | BRD4 | O60885 | 17/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748870 | 0.79 | BRD9 (0.57) | CECR2BRD9BRD4 | |
| SCHEMBL15069208 | 0.72 | BRD4 (0.58) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL24363723 | 0.71 | PDE4A (0.31) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL30143873 | 0.71 | CECR2 (0.50) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17749861 | 0.69 | BRD4 (1.00) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17752990 | 0.69 | TAF1 (0.55) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL19657249 | 0.69 | PDE4A (0.32) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL19658431 | 0.68 | CECR2 (0.49) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17758551 | 0.67 | CECR2 (0.81) | CECR2TAF1BRD9BRD4 | |
| SCHEMBL17749881 | 0.67 | CECR2 (1.00) | CECR2TAF1BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218375-B1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH INC (US) | 2022-04-27 | — | — | EP | disclosed |