Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398237 | 0.88 | NPC1 (0.47) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL12230559 | 0.76 | ALDH1A1 (0.62) | KDM4EALDH1A1NPC1RAB9ANQO2 | |
| SCHEMBL11983825 | 0.74 | NPC1 (0.46) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL15922168 | 0.73 | NPC1 (0.61) | KDM4EALDH1A1LMNAMAPK13GCGR | |
| SCHEMBL5539593 | 0.73 | KDM4E (0.52) | KDM4EALDH1A1LMNASLC9A1NPC1 | |
| SCHEMBL5539598 | 0.73 | GSK3B (0.57) | KDM4EALDH1A1LMNASLC9A1NPC1 | |
| SCHEMBL24670424 | 0.72 | HRH3 (0.50) | KDM4EALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3506668 | 0.72 | F2 (0.45) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13167116 | 0.72 | NPC1 (0.37) | KDM4EALDH1A1LMNAMAPK13GCGR | |
| SCHEMBL15827302 | 0.72 | NPC1 (0.45) | KDM4EALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545050-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | Bristol-Myers Squibb Company (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112186-A1 | COMPOUNDS FOR THE TREATMENT OF HEPATITIS C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-09-15 | — | — | WO | disclosed |