Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4654151 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL69159 | 0.79 | ALDH1A1 (0.58) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL3621051 | 0.78 | DHODH (0.51) | KDM4EALDH1A1GLAGAAHPGD | |
| Hydrochloric Acid SCHEMBL5553175 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL31622301 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| Hydrochloric Acid SCHEMBL29161457 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL29228925 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL2186719 | 0.77 | KDM4E (0.76) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL3979989 | 0.74 | ALDH1A1 (0.57) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL25332544 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106627-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |