Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.75 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.56 |
| ▸ | BRD4 | O60885 | 14/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482221 | 0.86 | CECR2 (1.00) | CECR2BRD9BRD4 | |
| SCHEMBL29482219 | 0.86 | CECR2 (1.00) | CECR2BRD9BRD4 | |
| SCHEMBL17749755 | 0.86 | CECR2 (1.00) | CECR2BRD9BRD4 | |
| SCHEMBL15069674 | 0.80 | BRD4 (0.78) | BRD4 | |
| SCHEMBL15069296 | 0.75 | BRD4 (0.74) | BRD4 | |
| SCHEMBL15069415 | 0.74 | BRD4 (0.74) | BRD4 | |
| SCHEMBL15069394 | 0.73 | BRD4 (0.68) | BRD4 | |
| SCHEMBL23436657 | 0.73 | BRD4 (0.77) | BRD4 | |
| SCHEMBL15069089 | 0.72 | BRD4 (0.71) | BRD4 | |
| SCHEMBL17749864 | 0.71 | BRD9 (1.00) | CECR2BRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3218375-B1 | SUBSTITUTED PYRROLOPYRDINES AS INHIBITORS OF BROMODOMAIN | GENENTECH INC (US) | 2022-04-27 | — | — | EP | disclosed |