⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436975 | 1.00 | — | — | |
| SCHEMBL2561668 | 0.72 | — | — | |
| SCHEMBL16671186 | 0.72 | — | — | |
| SCHEMBL18660170 | 0.72 | KDM4E (0.41) | — | |
| SCHEMBL235759 | 0.71 | KDM4E (0.36) | — | |
| SCHEMBL317785 | 0.71 | KDM4E (0.36) | — | |
| SCHEMBL20491396 | 0.70 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL10694337 | 0.68 | KDM4E (0.34) | — | |
| Hydrochloric Acid SCHEMBL10694332 | 0.68 | KDM4E (0.34) | — | |
| Ammonia Solution, Strong SCHEMBL9748105 | 0.68 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3403651-B1 | ISOCORYDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | LANZHOU INST CHEMICAL PHYSICS CAS (CN) | 2019-10-30 | — | — | EP | claimed |
| WO-2015057992-A1 | BTK INHIBITORS FOR HEMATOPOIETIC MOBILIZATION | IZUMI RAQUEL (US) | 2015-04-23 | — | — | WO | claimed |
| US-20130040934-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2013-02-14 | — | — | US | claimed |
| EP-2547684-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | University of Basel (CH) | 2013-01-23 | — | — | EP | claimed |
| WO-2011114275-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2011-09-22 | — | — | WO | claimed |
| WO-2015057992-A1 | BTK INHIBITORS FOR HEMATOPOIETIC MOBILIZATION | IZUMI RAQUEL (US) | 2015-04-23 | — | — | WO | disclosed |
| US-20130040934-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2013-02-14 | — | — | US | disclosed |
| EP-2547684-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | University of Basel (CH) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011114275-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2011-09-22 | — | — | WO | disclosed |
| EP-1472213-B1 | PROCESS FOR THE SYNTHESIS OF N-ACYL-2-AMINO-4-ALKOXY-5-NITROBENZOIC ACIDS | WYETH LLC (US) | 2010-06-09 | — | — | EP | disclosed |
| US-RE41253-E1 | Antineoplastic combinations | WYETH (US) | 2010-04-20 | — | — | US | disclosed |
| US-RE41084-E1 | Antineoplastic combinations | WYETH (US) | 2010-01-19 | — | — | US | disclosed |
| EP-1414438-B1 | ANTINEOPLASTIC COMBINATIONS | WYETH CORP (US) | 2005-12-28 | — | — | EP | disclosed |
| US-20050085662-A1 | Process for the synthesis of nacyl-2-amino-4-alkoxy-5-nitrobenzoic acids | WYETH (US) | 2005-04-21 | — | — | US | disclosed |
| EP-1472213-A1 | PROCESS FOR THE SYNTHESIS OF N-ACYL-2-AMINO-4-ALKOXY-5-NITROBENZOIC ACIDS | Wyeth (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1414438-A1 | ANTINEOPLASTIC COMBINATIONS | Wyeth (US) | 2004-05-06 | — | — | EP | disclosed |
| US-6617333-B2 | Rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methyl propionic acid (CCI-779) and 4-dimethylamino-but-2-enoic acid(4-(3-chloro-4-fluoro-phenylamino)-3-cyano-7-ethoxy-quinol in-6-yl)amide (EKB-569); synergistic; antitumor agents | WYETH | 2003-09-09 | — | — | US | disclosed |
| WO-2003066575-A1 | PROCESS FOR THE SYNTHESIS OF N-ACYL-2-AMINO-4-ALKOXY-5-NITROBENZOIC ACIDS | WYETH (US) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003020266-A1 | ANTINEOPLASTIC COMBINATIONS | WYETH (US) | 2003-03-13 | — | — | WO | disclosed |
| US-20030050222-A1 | Antineoplastic combinations | WYETH | 2003-03-13 | — | — | US | disclosed |