SCHEMBL24370064

SCHEMBL24370064

N#Cc1ccc(-n2c3ccccc3c3cc(-c4ccccc4-n4c5ccccc5c5ccccc54)ccc32)c(-c2ccncc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.37
CYP11B2 P19099 2/20 0.37
CYP19A1 P11511 2/20 0.37
PTGER4 P35408 1/20 0.37
FLT3 P36888 2/20 0.35
TNKS2 Q9H2K2 1/20 0.34
MAPK14 Q16539 3/20 0.34
GCGR P47871 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.33
SCN9A Q15858 1/20 0.33
CSNK1A1 P48729 1/20 0.33
CSNK1D P48730 1/20 0.33
SQOR Q9Y6N5 1/20 0.33
NAMPT P43490 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24370065 0.97 CYP11B1 (0.39) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL24369946 0.91 FLT3 (0.39) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL24370066 0.91 FLT3 (0.41) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL24369628 0.91 FLT3 (0.40) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL24369952 0.91 PTGER4 (0.39) PTGER4GABRA1GABRG2GABRB3GABRA5
SCHEMBL24369948 0.90 FLT3 (0.37) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL24370119 0.89 CYP19A1 (0.37) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL24370120 0.89 CYP19A1 (0.36) CYP11B1CYP11B2CYP19A1PTGER4FLT3
SCHEMBL24369953 0.88 PTGER4 (0.40) PTGER4GABRA1GABRG2GABRB3GABRA5
SCHEMBL24369959 0.87 PTGER4 (0.36) PTGER4GABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220131080-A1 CARBAZOLE DERIVATES FOR USE IN OPTOELECTRONIC DEVICES SIK3, ORAI3, HIPK3 CYP11B1 3064/4885CYP11B2 2487/4885CYP19A1 4651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.