Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750322 | 1.00 | CYP11B2 (0.41) | CYP11B2HRH3SLC6A4UTS2RAR | |
| SCHEMBL944838 | 0.93 | CYP11B2 (0.39) | CYP11B2HRH3SLC6A4UTS2RALK | |
| SCHEMBL28807605 | 0.92 | HRH3 (0.43) | CYP11B2HRH3SLC6A4UTS2RMEN1 | |
| SCHEMBL22717508 | 0.85 | SLC6A4 (0.38) | CYP11B2SLC6A4UTS2RALKMEN1 | |
| SCHEMBL19175494 | 0.79 | HRH3 (0.41) | CYP11B2HRH3SLC6A4ALKSLC6A2 | |
| SCHEMBL10088422 | 0.79 | HRH3 (0.44) | CYP11B2HRH3ARESRRA | |
| SCHEMBL1927148 | 0.78 | HRH3 (0.54) | HRH3ALKNR3C1 | |
| SCHEMBL1423702 | 0.76 | PTPN1 (0.36) | CYP11B2HRH3ARESRRANR3C1 | |
| SCHEMBL31750257 | 0.76 | HRH3 (0.44) | HRH3 | |
| SCHEMBL30118209 | 0.74 | AR (0.51) | SLC6A4ARALKMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262433-A1 | N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2025-12-26 | — | — | WO | disclosed |
| WO-2022084479-A1 | N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2022-04-28 | — | — | WO | disclosed |