SCHEMBL2437174

SCHEMBL2437174

O=S(=O)(Oc1ccc([S+](c2ccccc2)c2ccc(OS(=O)(=O)c3c(F)c(F)c(F)c(F)c3F)cc2)cc1)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
CA1 P00915 8/20 0.39
CA2 P00918 8/20 0.39
KMT2A Q03164 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CA12 O43570 3/20 0.37
CA7 P43166 3/20 0.37
CA13 Q8N1Q1 3/20 0.37
CA9 Q16790 3/20 0.35
MAPT P10636 4/20 0.33
MAOB P27338 1/20 0.33
ENPP3 O14638 2/20 0.32
ENPP1 P22413 2/20 0.32
ENPP2 Q13822 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4423397 1.00 TDP1 (0.40) TDP1CA1CA2KMT2ANPC1
Methane SCHEMBL4257313 0.98 TDP1 (0.39) TDP1CA1CA2KMT2ANPC1
Ethane SCHEMBL4847614 0.97 TDP1 (0.38) TDP1CA1CA2KMT2ANPC1
SCHEMBL2437745 0.95 TDP1 (0.37) TDP1CA1CA2KMT2ANPC1
SCHEMBL4839664 0.94 CA1 (0.36) TDP1CA1CA2KMT2ANPC1
Trifluoromethanesulfonic Acid SCHEMBL3422375 0.90 CA1 (0.34) TDP1CA1CA2KMT2ANPC1
SCHEMBL2439980 0.90 CA1 (0.34) TDP1CA1CA2KMT2ANPC1
SCHEMBL2439557 0.89 CA1 (0.34) TDP1CA1CA2KMT2ANPC1
SCHEMBL2436554 0.89 CA1 (0.34) TDP1CA1CA2KMT2ANPC1
SCHEMBL2437564 0.87 CA1 (0.33) TDP1CA1CA2KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2078028-B1 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA (US) 2011-09-07 EP claimed
US-7678528-B2 Photoactive compounds AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-03-16 US claimed
EP-2078028-A1 PHOTOACTIVE COMPOUNDS AZ Electronic Materials USA Corp. (US) 2009-07-15 EP claimed
WO-2008041123-A1 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-04-10 WO claimed
US-20070111138-A1 Photoactive compounds MERCK PATENT GMBH (DE) 2007-05-17 US claimed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-7833693-B2 Iodonium or sulfonium di-(tetrafluoroethyl sulfonate) ether acid generators; imaging negative and positive patterns in semiconductors and photoresists; microlithography; high photosensitivity AZ ELECTRONIC MATERIALS USA CORP. 2010-11-16 US disclosed
EP-2078028-A1 PHOTOACTIVE COMPOUNDS AZ Electronic Materials USA Corp. (US) 2009-07-15 EP disclosed
US-7521170-B2 Photoactive compounds AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-04-21 US disclosed
US-20090087782-A1 Iodonium or sulfonium di-(tetrafluoroethyl sulfonate) ether acid generators; imaging negative and positive patterns in semiconductors and photoresists; microlithography; high photosensitivity MERCK PATENT GMBH (DE) 2009-04-02 US disclosed
WO-2008041123-A1 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-04-10 WO disclosed