Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17958882 | 1.00 | TSHR (0.33) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL31228273 | 1.00 | TSHR (0.33) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL23818791 | 0.93 | TSHR (0.36) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL20756272 | 0.89 | TSHR (0.33) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL19221818 | 0.88 | ALDH1A1 (0.37) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL24498686 | 0.88 | ALDH1A1 (0.37) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL23906517 | 0.88 | TSHR (0.33) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL21063154 | 0.88 | ALDH1A1 (0.37) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL6838707 | 0.88 | TSHR (0.33) | TSHRALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL25400218 | 0.88 | TSHR (0.33) | TSHRALDH1A1TAAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3043803-B1 | NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND THEIR USES | UNIV EMORY (US) | 2022-04-27 | — | — | EP | disclosed |